The Africa Cup of Nations, known as the Total Africa Cup of Nations due to sponsorship, will start in Gabon on January 14.
The tournament, which features 16 teams and will last until February 5, was initially set to be hosted by Libya.
However, the Confederation of African Football rescinded their right to host the competition due to ongoing war in the country and Gabon were instead awarded the competition.
Gabon have qualified for the tournament as hosts and will face Burkina Faso, Cameroon and Guinea-Bissau in Group A.
Algeria, Tunisia, Senegal and Zimbabwe make up Group B, while Ivory Coast, DR Congo, Morocco and Togo make up Group C.
Group D will be comprised of Ghana, Mali, Egypt and Uganda.
A total of 24 Premier League players will jet off to the AFCON this month, leaving a total of 13 clubs short of players.
Sadio Mane will depart Liverpool to represent Senegal, while Mohamed Elneny will leave Arsenal to play for Egypt.
Leicester will also be adversely affected, with Riyad Mahrez and Islam Slimani set to represent Algeria and Daniel Amartey to play for Ghana.
Elsewhere, Eric Bailly will leave behind Manchester United, while Crystal Palace will lose both Bakary Sako and Wilfried Zaha, the latter of which opted against playing for England.
Burnley, Chelsea, Manchester City, Middlesbrough, Swansea City, Tottenham and West Brom are the Premier League clubs not represented.
The deadline for squads to be submitted is January 4 and FIFA rules state that players must be released by their clubs two days beforehand, unless special dispensation is required. As such, players representing their countries will be unable to play for their clubs this weekend, as the FA Cup third round gets underway.
